Key result
Major bleeding in CAD links to mortality risk matching MI, while early bleeds prove deadlier.
Why the study?
Does bleeding increase mortality compared to myocardial infarction in patients with coronary artery disease?
Does bleeding increase mortality compared to myocardial infarction in patients with coronary artery disease?
In patients with coronary artery disease, bleeding events carry a mortality risk that is similar to, or in the case of early bleeding, potentially greater than that of a myocardial infarction.
Bleeding prevention merits parity with MI avoidance in CAD management; extends meta-analytic evidence quantifying comparable mortality risks.
Compared with MI, major and late bleeding is associated with a similar increase in mortality, whereas early bleeding might have a stronger association with mortality.
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Piccolo et al. (2021) studied this question. Major and late bleeding in coronary artery disease patients is associated with similar mortality risk as myocardial infarction, while early bleeding has a stronger association.
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