What is the clinical evidence from this study?

Study design: Case Report. Population: Severe heart failure (n=1). Intervention: Cardiac resynchronization therapy (CRT-P). Primary outcome: Symptomatic improvement and functional independence.

What question did this study set out to answer?

This report aims to evaluate the effects of cardiac resynchronization therapy on a very elderly patient with severe heart failure.

February 12, 2026Case Reports in CardiologyOpen Access

Longevity and Innovation: Cardiac Resynchronization Therapy in a 100‐Year‐Old Patient With Severe Heart Failure—A 4‐Year Follow‐Up

Q: What does this research mean for the field?

Cardiac resynchronization therapy (CRT) significantly improves quality of life and functional independence in a 100-year-old patient with severe heart failure. Novelty: ClaimNovelty.NOVEL_FINDING. Consensus alignment: ConsensusAlignment.SUPPORTS_CONSENSUS.

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Key result

CRT-P improves symptoms and functional independence in a 100-year-old male with severe heart failure.

Why the study?

Does CRT-P improve symptoms and functional independence in a 100-year-old patient with severe heart failure, AF, and LBBB?

Population

A 100-year-old male with AF, LBBB, ischemic heart disease, chest pain, and bradycardia

Comparison

CRT-P implantation

Design

Case report

Follow-up

4 years

Authors

AHAyman HelalInterventional / Structural Cardiology IAIbrahim AntounUniversity of Leicester RPRachana Prasad

Discussion

Member takes

Implication

Supports CRT-P feasibility in centenarians with severe HF; hypothesis-generating and should not change practice.

Key Points

This report aims to evaluate the effects of cardiac resynchronization therapy on a very elderly patient with severe heart failure.
Patient presented with history of atrial fibrillation and ischemic heart disease.
Cardiac resynchronization therapy (CRT-P) successfully implanted.
Patient monitored closely for 4 years post-implantation.
Significant symptomatic improvement observed after CRT-P implantation.
Patient achieved functional independence during follow-up period.
CRT-P demonstrated effective management for heart failure in a 100-year-old patient.

Study Design

Type

Case Report (n=1)

Multicenter

Structured PICO

Does CRT-P improve symptoms and functional independence in a 100-year-old patient with severe heart failure, AF, and LBBB?

Population

100-year-old male with severe left ventricular systolic dysfunction, atrial fibrillation, left bundle branch block, and ischemic heart disease, admitted with chest pain and bradycardia (n=1)

Intervention

Cardiac resynchronization therapy pacemaker (CRT-P) implantation

Outcome

Symptomatic improvement and functional independencepatient reported

CRT-P implantation can provide significant symptomatic improvement and functional independence even in centenarian patients with severe heart failure.

Cite This Study

Helal et al. (2026) conducted a case report in Severe heart failure (n=1). Cardiac resynchronization therapy (CRT-P) was evaluated on Symptomatic improvement and functional independence. CRT-P implantation in a 100-year-old male with severe heart failure resulted in significant symptomatic improvement and functional independence over a 4-year follow-up.

synapsesocial.com/papers/698d6edc5be6419ac0d54ccb https://doi.org/10.1155/cric/7961581

Topics

Heart failure Atrial fibrillation Persistent AF management HFrEF treatment Heart failure hospitalization

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Longevity and Innovation: Cardiac Resynchronization Therapy in a 100‐Year‐Old Patient With Severe Heart Failure—A 4‐Year Follow‐Up

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Cite This Study

Topics

Longevity and Innovation: Cardiac Resynchronization Therapy in a 100‐Year‐Old Patient With Severe Heart Failure—A 4‐Year Follow‐Up

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Cite This Study

Also Consider

Topics

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