Why the study?
Older patients may be less likely to receive cardiac resynchronisation therapy (CRT) for heart failure, prompting an evaluation of differences in response, complications, and outcomes compared to younger patients.
Does age affect clinical response, complications, and outcomes following cardiac resynchronisation therapy in patients with heart failure?
Comparison
Patients aged <70 vs 70-79 vs ≥80 years
Design
Retrospective cohort study
Authors
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Supports CRT use in selected older patients; extends real-world evidence to octogenarians with comparable response despite comorbidities.
Does age affect clinical response, complications, and outcomes following cardiac resynchronisation therapy in patients with heart failure?
CRT provides similar symptomatic and echocardiographic benefits in older patients compared to younger patients, supporting its use in an ageing population despite higher baseline comorbidities.
Safdar et al. (2023) studied this question.
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