What question did this study set out to answer?

The aim is to assess how different timing of azasetron administration affects its ability to prevent postoperative nausea and vomiting (PONV) after laparoscopic surgery.

February 27, 2026Drug Design Development and TherapyOpen Access

Effects of Different Timing of Administration of Azasetron on the Prevention of Postoperative Nausea and Vomiting After Gynecological Laparoscopic Surgery: A Single Center, Double-Blind Randomized Controlled Trial

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Authors

ZLZicen LiDalian Medical University RZRuotong ZhaoDalian Medical University SCShiqi ChengDalian Medical University

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Implication

This randomized controlled trial evaluates azasetron's effectiveness in preventing nausea after gynecological surgery, highlighting timing's impact on outcomes.

Key Points

The aim is to assess how different timing of azasetron administration affects its ability to prevent postoperative nausea and vomiting (PONV) after laparoscopic surgery.
Conducted as a prospective randomized controlled trial.
Involved 129 patients undergoing elective laparoscopic gynecological surgery.
Participants were divided into three groups based on azasetron administration timing.
No significant differences in PONV incidence among the three groups during the 24-hour follow-up.
Rescue antiemetic demand was highest in the split-dose group (Group B).
PACU stay was significantly longer for Group B.

Cite This Study

Li et al. (2026) studied this question.

synapsesocial.com/papers/69a134fbed1d949a99abe6df https://doi.org/10.2147/dddt.s587239

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Implication

This randomized controlled trial evaluates azasetron's effectiveness in preventing nausea after gynecological surgery, highlighting timing's impact on outcomes.

Effects of Different Timing of Administration of Azasetron on the Prevention of Postoperative Nausea and Vomiting After Gynecological Laparoscopic Surgery: A Single Center, Double-Blind Randomized Controlled Trial

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Implication

Key Points

Cite This Study

Effects of Different Timing of Administration of Azasetron on the Prevention of Postoperative Nausea and Vomiting After Gynecological Laparoscopic Surgery: A Single Center, Double-Blind Randomized Controlled Trial

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Implication

Key Points

Cite This Study

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