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April 1, 1994Anaesthesia and Intensive Care

Ondansetron 4 mg for the Prevention of Nausea and Vomiting after Minor Laparoscopic Gynaecological Surgery

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Why the study?

Does intravenous ondansetron 4 mg prevent postoperative nausea and vomiting in Oriental women undergoing minor gynaecological laparoscopic surgery?

Population

Oriental women undergoing minor gynaecological laparoscopic surgery (n=204)

Comparison

Intravenous ondansetron 4 mg given before the… vs Placebo given before the induction of anaesthesia

Design

RCT, Randomised, Double-blind

Follow-up

24 hours

Authors

TST. K. L. SuenUniversity of Hong KongTGTony GinHospital AuthorityPCP. P. ChenChinese University of Hong Kong

Discussion

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Member takes

Overview

Supports ondansetron 4 mg IV for PONV prophylaxis; confirms efficacy in Oriental women after minor gynaecological laparoscopy.

Structured PICO

Does intravenous ondansetron 4 mg prevent postoperative nausea and vomiting in Oriental women undergoing minor gynaecological laparoscopic surgery?

P
Population
Oriental women undergoing minor gynaecological laparoscopic surgery (n=204)
I
Intervention
Intravenous ondansetron 4 mg given before the induction of anaesthesia
C
Comparator
Placebo given before the induction of anaesthesia
O
Outcome
Emetic episodes and nausea score (assessed using a verbal numeric scale from 0-10) over 24 hourspatient reported

Intravenous ondansetron 4 mg effectively reduces postoperative nausea and vomiting in women undergoing minor laparoscopic gynaecological surgery.

Cite This Study

Suen et al. (1994) studied this question.

synapsesocial.com/papers/6a8a85da3eb0001306cbeb49https://doi.org/10.1177/0310057x9402200203
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Ondansetron in the Treatment of Postoperative Vomiting1992 · 150 citations
  2. 2Postoperative Nausea and Vomiting1992 · 1,764 citations
  3. 3The effect of oral ondansetron in the prevention of postoperative nausea and vomiting after major gynaecological surgery performed under general anaesthesia1993 · 62 citations
  4. 4Antiemetic Efficacy of Ondansetron After Outpatient Laparoscopy1991 · 149 citations
  5. 5Treatment of Postoperative Nausea and Vomiting With Ondansetron1991 · 86 citations