Why the study?
Does targeted ablation of periostin-expressing activated fibroblasts prevent adverse cardiac remodeling in mice?
Does targeted ablation of periostin-expressing activated fibroblasts prevent adverse cardiac remodeling in mice?
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Targeted ablation of periostin-expressing activated fibroblasts is a promising preclinical approach to prevent adverse cardiac remodeling post-myocardial infarction and in response to angiotensin II.
Kaur et al. (2016) studied this question.
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