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March 6, 2026КАРДИОЛОГИЯ УЗБЕКИСТАНА3 citationsOpen Access

Prognostic Value of NT-proBNP in Patients Undergoing Tricuspid Valve Transcatheter Edge-to-Edge Repair: The EuroTR Registry

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JSJennifer von SteinPSPhilipp von SteinKKKarl‐Patrik Kresoja

Key Result

Baseline NT-proBNP independently predicted 2-year mortality or heart failure hospitalization after T-TEER, with early post-procedural changes adding prognostic value.

Key Points

  • The study aims to determine the prognostic value of NT-proBNP in predicting outcomes for patients post tricuspid valve repair.
  • Analyzed baseline NT-proBNP levels and post-procedural trajectories.
  • Included a cohort from the EuroTR registry.
  • Evaluated associations with 2-year mortality and heart failure hospitalization.
  • Baseline NT-proBNP was independently linked to increased 2-year mortality or heart failure hospitalization.
  • Post-procedural NT-proBNP trajectories offered additional prognostic insight.
  • Identified patients at greater risk of adverse outcomes.

Structured PICO

Does NT-proBNP level predict 2-year mortality or heart failure hospitalization in patients undergoing Tricuspid Valve Transcatheter Edge-to-Edge Repair?

P
Population
Patients undergoing Tricuspid Valve Transcatheter Edge-to-Edge Repair (T-TEER) in the EuroTR Registry
I
Intervention
Baseline and early post-procedural NT-proBNP measurement
O
Outcome
Composite of 2-year mortality or heart failure hospitalizationcomposite

Baseline and early post-procedural NT-proBNP levels provide significant prognostic value for predicting mortality and heart failure hospitalization in patients undergoing T-TEER.

Abstract

Baseline NT-proBNP was independently associated with 2-year mortality or heart failure hospitalization after T-TEER. Early post-procedural NT-proBNP trajectories provided incremental prognostic information and may identify patients at increased risk.

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Cite This Study

Stein et al. (2026) studied this question. Baseline NT-proBNP independently predicted 2-year mortality or heart failure hospitalization after T-TEER, with early post-procedural changes adding prognostic value.

synapsesocial.com/papers/69aa6f0d531e4c4a9ff592cahttps://doi.org/10.1016/j.jcin.2026.02.013
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