Key result
Community physician-led intervention links to an ~84% increase in BP control.
Why the study?
High-normal blood pressure in hypertensive patients confers cardiovascular risk and organ damage progression, but evidence regarding effective community-based interventions in this population is lacking.
Does a 12-month community physician-led health management intervention improve blood pressure control and lifestyle habits in hypertensive patients with high-normal blood pressure?
Does a 12-month community physician-led health management intervention improve blood pressure control and lifestyle habits in hypertensive patients with high-normal blood pressure?
Effect estimate: OR 3.222 for poor medication adherence due to adverse reactions as risk for uncontrolled BP (95% CI 1.169–8.878)
Absolute Event Rate: 36.3% vs 19.7%
p-value: p=<0.05
A 12-month community physician-led health management intervention significantly improves blood pressure control and promotes healthy lifestyle modifications in patients with high-normal blood pressure.
Supports community physician-led programs in routine high-normal BP care; extends prior evidence but leaves causality open pending RCTs.
Introduction Among patients with hypertension, maintaining blood pressure within the high-normal range is a common clinical scenario, often misinterpreted as adequate control. However, this level remains associated with cardiovascular risk and progression of target organ damage. Yet, evidence is lacking regarding effective community-based interventions in this population. This study aimed to evaluate the effects of a 12-month, community physician-led standardized health management intervention on blood pressure control rates, lifestyle improvements, and influencing factors in hypertensive patients with high-normal blood pressure, and to explore effective management strategies for this key population. Methods A series of information surveys and health interventions were conducted among 721 patients (aged 18–80 years) with high-normal blood pressure from communities in Shenyang. Descriptive analysis and multivariable logistic regression analysis were used as primary analytical methods. Results After 1 year of community intervention, both systolic and diastolic blood pressure significantly decreased in 721 individuals with high-normal blood pressure ( P < 0.05). Knowledge about hypertension, awareness of prevention, medication adherence, and behavioral adherence also improved compared to pre-intervention levels ( P < 0.05). A repeated-measures analysis of variance revealed a statistically significant main effect of time on both systolic and diastolic blood pressure [SBP: F (1.90 , 1, 369.92) = 135.833, partial η 2 = 0.159; DBP: F (1.995 , 1, 436.10) = 50.181, partial η 2 = 0.065, both P < 0.05]. Analysis of factors influencing blood pressure control at the end of the intervention demonstrated that poor medication adherence due to adverse drug reactions was associated with inadequate blood pressure control [OR (95% CI): 3.222 (1.169–8.878), P < 0.05]. Additionally, after the intervention, not reducing smoking was identified as a factor inversely associated with uncontrolled diastolic blood pressure [OR (95% CI): 0.192 (0.068–0.562), P < 0.05], while higher body weight remained associated with uncontrolled diastolic blood pressure [OR (95% CI): 1.018 (1.003–1.035), P < 0.05]. Furthermore, using non-drink-reducers as the reference group, alcohol reduction was identified as an influencing factor for uncontrolled systolic blood pressure [OR (95% CI): 2.550 (1.419–4.583), P < 0.05]. Conclusion Community-based interventions by primary care physicians targeting individuals with high-normal blood pressure can effectively modify unhealthy lifestyle habits and improve blood pressure control.
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Gao et al. (2026) studied Hypertensive patients aged 18-80 years with high-normal blood pressure (SBP 120-139 mmHg and/or DBP 80-89 mmHg) receiving community-based intervention in Shenyang, China (n=721). Community physician-led standardized health management intervention including health education, lifestyle modification counseling, medication adherence support vs. Pre-intervention baseline (same participants) was evaluated on Blood pressure control rate defined as average follow-up blood pressure <130/80 mmHg at 12 months post intervention (OR 3.222 for poor medication adherence due to adverse reactions as risk for uncontrolled BP, 95% CI 1.169–8.878, p=<0.05). Community physician-led intervention increased blood pressure control rate from 19.7% to 36.3% and significantly reduced median SBP from 132 to 130 mmHg and DBP from 78 to 76 mmHg after 12 months in hypertensive patients with high-normal BP.
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