What question did this study set out to answer?

This research aimed to evaluate the effectiveness of ondansetron in preventing nausea and vomiting after orthognathic surgery.

Ondansetron Prevents Nausea and Vomiting After Orthognathic Surgery

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Comparative analysis shows ondansetron reduces nausea and vomiting in surgery patients, suggesting effective postoperative care.

This research aimed to evaluate the effectiveness of ondansetron in preventing nausea and vomiting after orthognathic surgery.
Retrospective analysis of medical records from 291 patients.
Comparison of postoperative nausea and vomiting incidence using propensity score matching.
Focus on demographic factors, smoking history, and prior nausea and vomiting episodes.
PONV incidence decreased from 36% in the control group to 21% in the ondansetron group.
Statistical significance with P = .033 indicates a meaningful reduction.
No significant difference in postoperative headache incidence between groups.

Fujioka et al. (2026) studied this question.

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