Why the study?
The study was conducted to determine the efficacy of a single dose of ondansetron in preventing post-operative nausea and vomiting in general surgery patients.
Does a single dose of ondansetron prevent post-operative nausea and vomiting in general surgery patients?
Population
49 patients aged 20-60 years undergoing general surgery
Comparison
Single dose ondansetron 4 mg I/V before induction
Design
Cross-sectional study
Follow-up
24 hours
Authors
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Hypothesis-generating for single-dose ondansetron in PONV; larger randomized trials needed before clinical adoption.
Does a single dose of ondansetron prevent post-operative nausea and vomiting in general surgery patients?
A single 4 mg IV dose of ondansetron before induction appears effective in preventing post-operative nausea and vomiting in general surgery patients.
Naeem et al. (2021) studied this question.
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