This case report demonstrates platypnea-orthodeoxia syndrome caused by small bowel obstruction, suggesting a link to anatomical defects.
Platypnea-orthodeoxia syndrome (POS) is a rare condition in which positional change from recumbent to upright causes dyspnea and hypoxemia due to a cardiac or pulmonary shunt. Most cases require a primary anatomic defect and a secondary anatomic or functional factor that increases right-to-left shunting.
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Sullivan et al. (2026) studied this question.
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