The Extracellular Matrix in Ischemic and Nonischemic Heart Failure
Why the study?
The cell biological effectors mediating ECM remodeling and the molecular links between primary insults and matrix changes are poorly understood in conditions such as volume overload, diabetes mellitus, and obesity.
Design
Review article
Authors
Discussion
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Implication
May inform etiology-specific ECM interventions in HF; leaves open whether matrix-targeted therapies improve remodeling or regeneration.
Key Points
Key points are not available for this paper at this time.
Cite This Study
Nikolaos G. Frangogiannis (2019) studied this question.