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March 22, 2026MedicineOpen Access

An analysis of the global, regional, and national burden of liver cirrhosis in older adults from 1990 to 2021

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Authors

BHBo HuGCGuo ChenXCXian Chen

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Overview

Analysis reveals rising deaths and DALYs from liver cirrhosis in older adults, indicating significant global health disparities.

Key Points

  • This research assesses the burden of liver cirrhosis in older adults over three decades across multiple socio-economic levels.
  • Utilized data from the Global Burden of Disease Study 2021
  • Extracted death and DALY estimates for older adults aged 65 and above
  • Applied Joinpoint regression analysis to identify trends from 1990 to 2021
  • Deaths from liver cirrhosis increased over the study period
  • Age-standardized death rate declined annually with an average percentage change of −1.23
  • Higher burden of cirrhosis observed in middle and low-middle socio-demographic index regions

Cite This Study

Hu et al. (2026) studied this question.

synapsesocial.com/papers/69bf390ac7b3c90b18b433d2https://doi.org/10.1097/md.0000000000047933
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