Antibody Response to Poliomyelitis Vaccine Administered by Jet Injection

Anyone who must undertake the immunization of large numbers of persons with poliomyelitis vaccine will be interested in this report. It describes the results obtained with the use of a multiple-dose jet injector for parenteral administration of biologicals into subcutaneous fat or muscle tissue. Antibody response to two doses of poliomyelitis vaccine administered by a jet injector was comparable to that resulting from injection by needle. The former is the more economical and less time consuming procedure. The relative advantages and disadvantages of the two methods are discussed. The impression is gained from this article that the use of a jet injector is practicable for large-scale immunizations with poliomyelitis vaccine.