Silver‐Catalyzed Radical Addition/Cyclization Cascade Reaction to Access Sulfonylated 4‐Amino‐2‐quinolone Derivatives

Key Points

• The aim is to synthesize sulfonylated 4-amino-2-quinolone derivatives using a radical addition/cyclization reaction.
• Utilized ortho-cyanoarylacrylamides and sodium sulfinates as starting materials
• Employed silver as a catalyst to facilitate the reaction
• Demonstrated the method's scalability in producing the desired compounds
• Achieved good to excellent yields of sulfonylated 4-amino-2-quinolone derivatives
• The method tolerated various substrates, showcasing its versatility