Routine clinical variables, particularly diabetes, are strong independent predictors of mortality and morbidity in patients with chronic heart failure regardless of ejection fraction.
May aid HF risk stratification across EF spectra; leaves open prospective validation before guiding care.
In a large contemporary CHF population, including patients with preserved and decreased left ventricular systolic function, routine clinical variables can discriminate risk regardless of EF. Diabetes was found to be a surprisingly strong independent predictor. These models can stratify risk and help define how patient characteristics relate to clinical course.
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Pocock et al. (2005) studied this question.