July 17, 2017Open Access

Relationship between microvascular obstruction and adverse events following primary percutaneous coronary intervention for ST-segment elevation myocardial infarction: an individual patient data pooled analysis from seven randomized trials

Structured PICO

Does the presence and extent of microvascular obstruction measured by CMR predict mortality and heart failure hospitalization in patients following primary PCI for STEMI?

Population

Patients with ST-segment elevation myocardial infarction (STEMI) following primary percutaneous coronary intervention (PCI), pooled from 7 randomized trials.

Intervention

Presence and extent of microvascular obstruction (MVO) measured by cardiovascular magnetic resonance (CMR)

Comparator

Absence or lesser extent of microvascular obstruction

Outcome

Mortality and hospitalization for heart failure (HF) within 1 yearhard clinical

The presence and extent of microvascular obstruction on CMR after primary PCI for STEMI is a strong prognostic marker for 1-year mortality and heart failure hospitalization.

Abstract

The presence and extent of MVO measured by CMR after primary PCI in STEMI are strongly associated with mortality and hospitalization for HF within 1 year.

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