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May 16, 2011Journal of Internal MedicineOpen Access

Plasma carotenoids are related to intima - media thickness of the carotid artery wall in men from eastern Finland

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Why the study?

Are high plasma concentrations of specific carotenoids associated with decreased carotid intima-media thickness in elderly men?

Population

Elderly men from eastern Finland

Design

Cross-sectional

Authors

JKJouni KarppiSKSudhir KurlJLJari A. Laukkanen

Discussion

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Overview

Hypothesis-generating for carotenoid assessment in elderly men; leaves open randomized trials before practice change.

Structured PICO

Are high plasma concentrations of specific carotenoids associated with decreased carotid intima-media thickness in elderly men?

P
Population
Elderly men from eastern Finland
I
Intervention
High plasma concentrations of β-cryptoxanthin, lycopene and α-carotene
O
Outcome
Intima-media thickness of the carotid artery wall (carotid atherosclerosis)surrogate

Higher plasma levels of specific carotenoids are associated with reduced carotid intima-media thickness in elderly Finnish men.

Cite This Study

Karppi et al. (2011) studied this question.

synapsesocial.com/papers/69d56eef75589c71d767d7d3https://doi.org/10.1111/j.1365-2796.2011.02401.x
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Serum Carotenoids Reduce Progression of Early Atherosclerosis in the Carotid Artery Wall among Eastern Finnish Men2013 · 55 citations
  2. 2Progression of Carotid Intima-Media Thickness and Plasma Antioxidants: The Los Angeles Atherosclerosis Study2003 · 132 citations
  3. 3Total carotene plasma concentrations are inversely associated with atherosclerotic plaque burden: A post-hoc analysis of the DIABIMCAP cohort2023 · 5 citations
  4. 4Higher dietary and serum carotenoid levels are associated with lower carotid intima–media thickness in middle-aged and elderly people2018 · 20 citations
  5. 5Circulating Lycopene and β-Carotene Levels Are Inversely Associated with Carotid Intima–Media Thickness: A Systematic Review and Meta-Analysis2026