Why the study?
Does radiation therapy increase the risk of clinically significant valvular heart disease in patients treated for Hodgkin Lymphoma?
Population
Patients treated for Hodgkin Lymphoma with mediastinal involvement
Design
Cohort
Follow-up
30 years
Authors
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Supports cardiac surveillance in HL survivors after mediastinal RT; leaves open optimal long-term screening protocols.
Does radiation therapy increase the risk of clinically significant valvular heart disease in patients treated for Hodgkin Lymphoma?
Modern radiation doses of 20-30 Gy for Hodgkin lymphoma with mediastinal involvement carry a small (1.4%) increased 30-year risk of clinically significant valvular heart disease.
Cutter et al. (2015) studied this question.
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