Why the study?
Does superoxide dismutase therapy reduce reperfusion injury in animal models of myocardial ischemia?
Does superoxide dismutase therapy reduce reperfusion injury in animal models of myocardial ischemia?
While superoxide dismutase and other antioxidants can reduce reperfusion-induced arrhythmias and stunning in animal models, they do not prevent irreversible myocardial infarction.
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Reduces arrhythmias and stunning but not infarct size in animal models; leaves open clinical translation of antioxidant therapy.
Downey et al. (1991) studied this question.
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