Why the study?
Is hypertensive left ventricular hypertrophy associated with increased cardiac sympathetic activity?
Is hypertensive left ventricular hypertrophy associated with increased cardiac sympathetic activity?
Hypertensive left ventricular hypertrophy is associated with localized increases in cardiac sympathetic activity and norepinephrine release.
Hypothesis-generating for cardiac sympathetic modulation in hypertensive LVH; prospective trials needed to assess causality.
Our findings demonstrate that hypertensive LV hypertrophy is associated with increased sympathetic activity largely confined to the heart, suggesting that increased cardiac norepinephrine release is related to the development of LV hypertrophy.
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Schlaich et al. (2003) studied this question.
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