Why the study?
Lower heart rate variability is associated with cardiovascular events and mortality, but the extent of this association in patients with cardiovascular disease remained uncertain.
Does lower heart rate variability increase the risk of all-cause death and cardiovascular events in patients with cardiovascular disease?
Population
3,094 participants with CVD across 28 cohort studies
Comparison
Lower HRV vs higher HRV
Design
Meta-analysis of cohort studies
Follow-up
At least 1 year
Authors
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Supports HRV for risk stratification in CVD patients; confirms prognostic value but should not yet change practice.
Does lower heart rate variability increase the risk of all-cause death and cardiovascular events in patients with cardiovascular disease?
Lower heart rate variability is a significant prognostic marker for increased all-cause mortality and cardiovascular events in patients with cardiovascular disease, particularly following acute myocardial infarction.
Fang et al. (2019) studied this question.
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