Correlation with Invasive Left Ventricular Filling Pressures and Prognostic Relevance of the Echocardiographic Diastolic Parameters Used in the 2016 Esc Heart Failure Guidelines and in the 2016 Ase/Eacvi Recommendations: A Systematic Review in Patients with Heart Failure with Preserved Ejection Fraction
Why the study?
Do echocardiographic diastolic parameters correlate with invasive left ventricular filling pressures and outcomes in patients with HFpEF?
Population
Patients with Heart Failure with Preserved Ejection Fraction (HFpEF)
Comparison
Echocardiographic diastolic parameters at rest vs Invasive left ventricular filling pressures
Design
Systematic_review
Authors
Discussion
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Member takes
Implication
Limits reliance on E/e' for HFpEF assessment; challenges non-invasive diagnostic criteria and prompts better parameter validation.
Structured PICO
Do echocardiographic diastolic parameters correlate with invasive left ventricular filling pressures and outcomes in patients with HFpEF?
P
Population
Patients with Heart Failure with Preserved Ejection Fraction (HFpEF)
I
Intervention
Echocardiographic diastolic parameters at rest (specifically E/e' as per 2016 ESC and ASE/EACVI guidelines)
C
Comparator
Invasive left ventricular filling pressures
O
Outcome
Correlation with invasive filling pressures and outcomessurrogate
The widely used echocardiographic parameter E/e' has only modest correlation with invasive filling pressures and outcomes in HFpEF, suggesting limitations in current non-invasive diagnostic criteria.
Limitations
- Only a small number of studies validated the use of echocardiographic parameters at rest in patients with HFpEF
Cite This Study
Nauta et al. (2018) studied this question.