Why the study?
Does 1 year of exercise training reduce LV myocardial stiffness in patients with stage B heart failure with preserved ejection fraction?
Does 1 year of exercise training reduce LV myocardial stiffness in patients with stage B heart failure with preserved ejection fraction?
One year of exercise training reduces LV myocardial stiffness in patients with stage B HFpEF, potentially offering protection against progression to symptomatic heart failure.
Exercise may lower LV stiffness in stage B HFpEF; leaves open effects on progression and needs RCTs.
In patients with LV hypertrophy and elevated cardiac biomarkers (stage B heart failure with preserved ejection fraction), 1 year of exercise training reduced LV myocardial stiffness. Thus, exercise training may provide protection against the future risk of heart failure with preserved ejection fraction in such patients. Registration: URL: https://www.clinicaltrials.gov; Unique identifier: NCT03476785.
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Hieda et al. (2021) studied this question.
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