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April 8, 2026Al-Azhar Assiut Medical JournalOpen Access

Spondylosis severity correlates with increased carotid intima-media thickness, revealing subclinical atherosclerosis in 14% of patients.

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Why the study?

Is spondylosis severity associated with subclinical atherosclerosis measured by carotid intima-media thickness?

Population

100 patients with lumbar and/or cervical spondylosis and low back and/or cervical pain

Comparison

Spondylosis severity assessed for association with carotid intima-media thickness

Design

Cross-sectional study

Key result

Subclinical atherosclerosis was found in 14% of spondylosis patients, and carotid intima-media thickness significantly correlated with lumbar (r=0.41) and cervical (r=0.32) spondylosis severity.

Authors

SHSara M. HasanAMAbdelhfeez MoshrifMSMohamed Z. Shoaeir

Discussion

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Overview

May warrant CV risk assessment in severe spondylosis; leaves open causality pending prospective validation.

Key Points

  • This study aims to investigate the connection between spondylosis and subclinical atherosclerosis.
  • Conducted a cross-sectional study with 100 patients having lumbar and/or cervical spondylosis.
  • Used radiographic evaluation based on the Lane and Kellgren indices.
  • Measured carotid intima-media thickness to assess subclinical atherosclerosis.
  • Applied correlation and regression analyses to explore associations.
  • Subclinical atherosclerosis found in 14% of participants.
  • CIMT significantly correlated with age, cervical pain severity, and Lane index (r = 0.72, 0.34, 0.41; P < 0.001).
  • Additional correlations identified between CIMT and triglyceride levels, Roland-Morris score, and Kellgren index (r = 0.25, 0.23, 0.32; P = 0.014).

Structured PICO

Is spondylosis severity associated with subclinical atherosclerosis measured by carotid intima-media thickness?

P
Population
100 patients with lumbar and/or cervical spondylosis presenting with low back and/or cervical pain
O
Outcome
Subclinical atherosclerosis evaluated through the measurement of carotid intima-media thickness (CIMT) using Doppler ultrasonographysurrogate

Severe lumbar and cervical spondylosis is associated with a higher prevalence of subclinical atherosclerosis as measured by carotid intima-media thickness.

Limitations

  • small sample size
  • single-center

Cite This Study

Hasan et al. (2026) studied this question. Subclinical atherosclerosis was found in 14% of spondylosis patients, and carotid intima-media thickness significantly correlated with lumbar (r=0.41) and cervical (r=0.32) spondylosis severity.

synapsesocial.com/papers/69d5f07d74eaea4b11a79f6ehttps://doi.org/10.4103/azmj.azmj_99_25
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