Why the study?
Does the addition of acetazolamide to loop diuretic therapy improve successful decongestion in patients with acute decompensated heart failure with volume overload?
Does the addition of acetazolamide to loop diuretic therapy improve successful decongestion in patients with acute decompensated heart failure with volume overload?
Adding acetazolamide to standard loop diuretic therapy improves the incidence of successful decongestion in patients with acute decompensated heart failure.
May support adding acetazolamide for decongestion in acute decompensated HF; extends evidence for adjunctive diuretic strategies.
The addition of acetazolamide to loop diuretic therapy in patients with acute decompensated heart failure resulted in a greater incidence of successful decongestion. (Funded by the Belgian Health Care Knowledge Center; ADVOR ClinicalTrials.gov number, NCT03505788.).
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Müllens et al. (2022) studied this question.
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