What question did this study set out to answer?

The aim was to compare the safety and efficacy of oxandrolone with somatropin/testosterone in adult patients with severe burns.

Safety and Efficacy of Oxandrolone vs Somatropin/Testosterone in Adult Patients with Severe Burns

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This observational study compares oxandrolone and somatropin/testosterone outcomes in adult burn patients, indicating noninferiority of treatments.

The aim was to compare the safety and efficacy of oxandrolone with somatropin/testosterone in adult patients with severe burns.
Conducted at an ABA-accredited burn center.
Used a retrospective, observational, cohort design.
Included two treatment arms: oxandrolone and somatropin/testosterone.
Collected data on length of stay, safety outcomes, and patient demographics.
No significant difference in length of stay between oxandrolone (35 days) and somatropin/testosterone (30 days, p=.787).
20% of oxandrolone patients had hepatic dysfunction needing dose adjustments vs. 9.5% in the somatropin/testosterone group (p=.125).
Reported hyperglycemia in 60% of somatropin patients.
Mortality rates were similar: 15% for oxandrolone vs. 24% for somatropin/testosterone (p=.697).
Change in weight showed no significant difference: -2.6 lbs for oxandrolone vs. -0.77 lbs for somatropin/testosterone (p=.598).

Terrell et al. (2026) studied this question.

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This observational study compares oxandrolone and somatropin/testosterone outcomes in adult burn patients, indicating noninferiority of treatments.