What question did this study set out to answer?

To determine whether colloidal graphite surfaces treated with a cationic surfactant can bind heparin and resist clot formation.

December 6, 1963Science

Heparin Bonding on Colloidal Graphite Surfaces

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To determine whether colloidal graphite surfaces treated with a cationic surfactant can bind heparin and resist clot formation.
Treated colloidal graphite surfaces with a cationic, surface-active agent to facilitate the bonding of heparin.
Conducted in vitro and in vivo clotting assays to compare the performance of graphite-heparin surfaces with standard plastic and silicone surfaces.
Colloidal graphite rinsed with a cationic surfactant successfully established heparin bonding.
Graphite-heparin surfaces exhibited markedly greater resistance to clot formation than either plastic or silicone surfaces in comparative testing.

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Implication

Preclinical study shows enhanced clot resistance on heparin-bonded colloidal graphite surfaces, indicating improved biocompatibility over plastic or silicone.

Cite This Study

Gott et al. (1963) studied this question.

synapsesocial.com/papers/69d96a40c7f0c3ae80a3d63e https://doi.org/10.1126/science.142.3597.1297

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Implication

Preclinical study shows enhanced clot resistance on heparin-bonded colloidal graphite surfaces, indicating improved biocompatibility over plastic or silicone.

Heparin Bonding on Colloidal Graphite Surfaces

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Discussion

Implication

Cite This Study

Heparin Bonding on Colloidal Graphite Surfaces

Key Points

Discussion

Implication

Cite This Study

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