Does NT-proBNP testing accurately diagnose heart failure in people with atrial fibrillation compared to those without?
NT-proBNP testing is less accurate for diagnosing heart failure in patients with atrial fibrillation compared to those without, complicating the use of adjusted referral thresholds.
NT-proBNP discriminates more accurately for HF among people without AF than with AF. A higher referral threshold could be considered in AF to account for higher median NT-proBNP levels but this would also increase missed HF diagnoses.
Jones et al. (Thu,) studied this question.