Accurate calling of KIAA1549‐BRAF fusions from DNA of human brain tumours using methylation array‐based copy number and gene panel sequencing data

Damian Stichel; Daniel Schrimpf; Philipp Sievers; Annekathrin Reinhardt; Abigail K. Suwala; Martin Sill; David Reuß; Andrey Korshunov; Belén Casalini; Alexander C. Sommerkamp; Jonas Ecker; Florian Selt; Dominik Sturm; Astrid Gnekow; Arend Koch; Michèle Simon; Pablo Hernáiz Driever; Ulrich Schüller; David Capper; Cornelis M. van Tilburg; Olaf Witt; Till Milde; Stefan M. Pfister; David Jones; Andreas von Deimling; Felix Sahm; Annika K. Wefers

doi:10.1111/nan.12683

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Abstract

The KIAA1549-BRAF fusion can be reliably detected from either DNA methylation array or DNA panel data. The use of both methods is recommended for the most sensitive detection of this diagnostically and therapeutically important marker.

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Stichel et al. (2020) studied this question.

synapsesocial.com/papers/69dd443bfb7610310c1016c2 https://doi.org/10.1111/nan.12683

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Accurate calling of KIAA1549‐BRAF fusions from DNA of human brain tumours using methylation array‐based copy number and gene panel sequencing data

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Abstract

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Accurate calling of KIAA1549‐BRAF fusions from DNA of human brain tumours using methylation array‐based copy number and gene panel sequencing data

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Abstract

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Cite This Study

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