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April 16, 2026Food Safety and HealthOpen Access

Genomic Insights Into Spatiotemporal Dynamics of Acquired Azithromycin Resistance Genes in Salmonella Strains Worldwide

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Authors

YPYuhang PeiMQMengqi QuZYZiru Yang

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Overview

Global genomic analysis reveals increasing azithromycin resistance in Salmonella, indicating a rise in public health concerns.

Key Points

  • This study aims to analyze the global distribution and trends of azithromycin resistance genes in Salmonella strains.
  • Analyzed 260,195 Salmonella genomes with metadata
  • Conducted in silico analysis to assess resistance genes
  • Performed phylogenetic analysis of resistant strains
  • 1.28% of Salmonella strains carried azithromycin resistance genes
  • mph(A) was the dominant resistance gene observed globally
  • Increasing trends of mph(A) were noted in various environments and species
  • Co-occurrence of resistance genes with last-line antibiotics was documented
  • Significant findings were identified in Salmonella serovars from different continents

Cite This Study

Pei et al. (2026) studied this question.

synapsesocial.com/papers/69e07dfe2f7e8953b7cbef20https://doi.org/10.1002/fsh3.70099
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Global genomic surveillance uncovers emergence and spatiotemporal patterns of World Health Organization priority antibiotic resistance in invasive Salmonella2026 · 3 citations
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  5. 5Epidemiology and genomics of azithromycin-resistant extensively drug-resistant <i>Salmonella enterica</i> serovar Typhimurium in Taiwan2026