What question did this study set out to answer?

This study evaluates the prognostic significance of bone marrow plasma cell infiltration at diagnosis in AL amyloidosis patients.

April 19, 2026SHILAP Revista de lepidopterologíaOpen Access

B02 | the Prognostic Impact of Bone Marrow Plasma Cell Infiltration at Diagnosis in Al Amyloidosis

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Authors

KAK. AslantaşAnkara University ŞÖŞ. ÖzlüAnkara University IKI. KuzuAnkara University

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Implication

Retrospective analysis shows BMPC infiltration predicts treatment response and survival in AL amyloidosis, implying its use in clinical decision-making.

Key Points

This study evaluates the prognostic significance of bone marrow plasma cell infiltration at diagnosis in AL amyloidosis patients.
Retrospective analysis of 116 AL amyloidosis patients diagnosed between 2010 and 2024.
Patients divided into two groups based on BMPC infiltration rate: ≤10% and >10%.
Evaluated clinical features, organ involvement, treatment responses, and survival outcomes using statistical methods.
Patients with BMPC >10% had higher levels of involved free light chains and worse disease stage.
Median overall survival was 56 months for BMPC ≤10% and 16 months for BMPC >10%.
BMPC infiltration >10% was identified as an independent predictor of early mortality and worse overall survival.

Cite This Study

Aslantaş et al. (2026) studied this question.

synapsesocial.com/papers/69e4702d010ef96374d8d6e0 https://doi.org/10.3324/haematol.2026.s2.14048

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Implication

Retrospective analysis shows BMPC infiltration predicts treatment response and survival in AL amyloidosis, implying its use in clinical decision-making.

B02 | the Prognostic Impact of Bone Marrow Plasma Cell Infiltration at Diagnosis in Al Amyloidosis

Discussion

Member takes

Implication

Key Points

Cite This Study

B02 | the Prognostic Impact of Bone Marrow Plasma Cell Infiltration at Diagnosis in Al Amyloidosis

Discussion

Member takes

Implication

Key Points

Cite This Study

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