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April 22, 2026Clinical Cardiology0 citationsOpen Access

Enhancing Heart Failure Detection in the General Population Using the Steatosis‐Associated Fibrosis Estimator

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WSWenrui ShiChinese Academy of Medical Sciences & Peking Union Medical CollegeYSYangbin ShiShanghai Jiao Tong UniversityJPJieun ParkShanghai Jiao Tong University

Key Result

The Steatosis-Associated Fibrosis Estimator (SAFE) showed a nearly linear and robust relationship with prevalent heart failure in the general population.

Key Points

  • This study aims to evaluate the relationship between the Steatosis‐Associated Fibrosis Estimator (SAFE) and the prevalence of heart failure (HF).
  • Analyzed the correlation between SAFE and heart failure incidences
  • Focused on the general population for applicability
  • Utilized statistical evaluations to support findings
  • Identified a nearly linear relationship between SAFE scores and prevalent HF cases
  • Demonstrated that SAFE may enhance HF detection efforts
  • Suggests potential for broad use in screening strategies

Structured PICO

Does the Steatosis-Associated Fibrosis Estimator (SAFE) improve the detection of prevalent heart failure in the general population?

P
Population
General population
I
Intervention
Steatosis-Associated Fibrosis Estimator (SAFE)
O
Outcome
Prevalent heart failure (HF)

The Steatosis-Associated Fibrosis Estimator (SAFE) may serve as a useful indicator for enhancing heart failure detection in the general population.

Abstract

This study identified a nearly linear and robust relationship between SAFE and prevalent HF, suggesting that SAFE may serve as a useful indicator for enhancing HF detection in the general population.

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Cite This Study

Shi et al. (2026) studied this question. The Steatosis-Associated Fibrosis Estimator (SAFE) showed a nearly linear and robust relationship with prevalent heart failure in the general population.

synapsesocial.com/papers/69e865126e0dea528dde9b24https://doi.org/10.1002/clc.70318
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