Demonstrates the synthesis of alkylated pyrazolones, suggesting a new method for compound development.
We report a photoinduced palladium-catalyzed protocol for the synthesis of biologically relevant alkylated and difluoroalkylated pyrazolones via a radical cascade between N'-arylidene-N-acryloylphenylhydrazides and unactivated alkyl and difluoroalkyl halides. Mechanistic studies...
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Das et al. (2026) studied this question.
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