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April 26, 2026BMC MicrobiologyOpen Access

High prevalence of blaNDM gene among a series of carbapenem-resistant Enterobacterales isolates from children less than one year old in Niger

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Authors

IMIssoufou Noma MassirLaboratoire National de RéférenceYAYacouba AbdourahamaneUniversité Abdou MoumouniTOTapha OunoussaLaboratoire National de Référence

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Overview

Prospective case series reveals high blaNDM prevalence in carbapenem-resistant Enterobacterales, indicating critical resistance challenges in infants.

Key Points

  • To evaluate the molecular epidemiology and antimicrobial susceptibility of carbapenem-resistant Enterobacterales in infants under one year in Niger.
  • Analyzed 14 isolates from children under one year old.
  • Identified bacterial species and detected carbapenemase genes.
  • Assessed antimicrobial susceptibility to various antibiotics.
  • 50.0% of isolates contained the blaNDM gene.
  • High resistance rates to fluoroquinolones and aminoglycosides were observed.
  • Cefiderocol showed preserved activity across carbapenemase genotypes.

Cite This Study

Massir et al. (2026) studied this question.

synapsesocial.com/papers/69edab424a46254e215b355ehttps://doi.org/10.1186/s12866-026-05094-5
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