Why the study?
Does a diminished nocturnal decline in blood pressure increase the risk of cardiovascular mortality in the general population?
Does a diminished nocturnal decline in blood pressure increase the risk of cardiovascular mortality in the general population?
A diminished nocturnal decline in blood pressure independently predicts cardiovascular mortality in the general population, regardless of 24-hour blood pressure load.
May enhance CV risk stratification beyond 24-h load; leaves open whether targeting nocturnal dipping improves outcomes.
This is the first study to demonstrate that a diminished nocturnal decline in blood pressure is a risk factor for cardiovascular mortality, independent of the overall blood pressure load during a 24-h period, in the general population.
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Ohkubo et al. (2002) studied this question.
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