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May 11, 1999Circulation2,142 citationsOpen Access

Impact of Aortic Stiffness on Survival in End-Stage Renal Disease

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JBJacques BlacherAGAlain P. GuérinBPBruno Pannier

Key Points

  • This research aims to investigate the relationship between aortic stiffness and mortality rates in patients with end-stage renal disease (ESRD).
  • Measurement of aortic stiffness using pulse wave velocity (PWV)

Structured PICO

Does increased aortic stiffness predict all-cause and cardiovascular mortality in patients with end-stage renal disease?

P
Population
patients with end-stage renal disease (ESRD)
I
Intervention
increased aortic stiffness determined by measurement of aortic pulse wave velocity (PWV)
O
Outcome
all-cause and cardiovascular mortalityhard clinical

Aortic stiffness measured by pulse wave velocity is a strong independent predictor of mortality in patients with end-stage renal disease.

Abstract

These results provide the first direct evidence that in patients with ESRD, increased aortic stiffness determined by measurement of aortic PWV is a strong independent predictor of all-cause and mainly cardiovascular mortality.

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Cite This Study

Blacher et al. (1999) studied this question.

synapsesocial.com/papers/69eede7da84321e0ae63c444https://doi.org/10.1161/01.cir.99.18.2434
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