Key result
Increased aortic stiffness predicts all-cause and CV mortality in patients with ESRD.
Why the study?
In patients with ESRD, the prognostic value of increased aortic stiffness measured by aortic PWV for mortality was not previously established.
Does increased aortic stiffness predict all-cause and cardiovascular mortality in patients with end-stage renal disease?
Does increased aortic stiffness predict all-cause and cardiovascular mortality in patients with end-stage renal disease?
Aortic stiffness measured by pulse wave velocity is a strong independent predictor of mortality in patients with end-stage renal disease.
May refine ESRD mortality risk stratification; extends observational data but leaves open whether targeting stiffness improves outcomes.
These results provide the first direct evidence that in patients with ESRD, increased aortic stiffness determined by measurement of aortic PWV is a strong independent predictor of all-cause and mainly cardiovascular mortality.
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Blacher et al. (1999) studied this question. Increased aortic stiffness, measured by aortic pulse wave velocity, is a strong independent predictor of all-cause and cardiovascular mortality in patients with end-stage renal disease.
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