What question did this study set out to answer?

This research investigates how selecting embryos that develop faster affects their sex ratios and metabolic characteristics. It specifically looks at molecular profiles in bovine in vitro produced embryos.

April 27, 2026ReproductionOpen Access

Selection for Developmental Speed Skews Sex Ratios and Metabolic Profiles in Bovine IVP Embryos

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Authors

VBVijay Simha BaddelaResearch Institute for Farm Animal Biology (FBN)TFTheres FerstererResearch Institute for Farm Animal Biology (FBN)RPRalf PöhlandResearch Institute for Farm Animal Biology (FBN)

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Implication

Randomized trial shows selection for rapid embryo development impacts sex ratios and metabolic profiles in bovine embryos, suggesting potential implications for herd management.

Key Points

This research investigates how selecting embryos that develop faster affects their sex ratios and metabolic characteristics. It specifically looks at molecular profiles in bovine in vitro produced embryos.
Analyzed hatching-stage blastocysts developed on Day 7 and Day 8 using RNA-sequencing and metabolic assessments.
Performed sexing via Y-chromosome multiplex PCR and quantified candidate gene expression by qPCR for individually sexed embryos.
Assessed lipid content, mitochondrial activity, and reactive oxygen species levels between groups.
RNA-sequencing identified 192 differentially expressed genes, with Day 8 embryos showing higher expression of pregnancy recognition factors.
Day 7 embryos had significantly higher lipid content, but comparable mitochondrial activity and ROS levels to Day 8.
Sexing analysis indicated a significant male bias with 66.7% male on Day 7 and 58.5% on Day 8.

Cite This Study

Baddela et al. (2026) studied this question.

synapsesocial.com/papers/69eefde9fede9185760d4abe https://doi.org/10.1093/reprod/xaag048

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Implication

Randomized trial shows selection for rapid embryo development impacts sex ratios and metabolic profiles in bovine embryos, suggesting potential implications for herd management.

Selection for Developmental Speed Skews Sex Ratios and Metabolic Profiles in Bovine IVP Embryos

Discussion

Member takes

Implication

Key Points

Cite This Study

Selection for Developmental Speed Skews Sex Ratios and Metabolic Profiles in Bovine IVP Embryos

Discussion

Member takes

Implication

Key Points

Cite This Study

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