Why the study?
Are major ventricular arrhythmias associated with sustained and selective cardiac sympathetic activation?
Are major ventricular arrhythmias associated with sustained and selective cardiac sympathetic activation?
Sustained ventricular arrhythmias may be driven by reflex cardiac sympathetic activation secondary to depressed ventricular function.
May support sympathetic modulation in ventricular arrhythmia management; leaves open causality and need for prospective trials.
These results suggest that in some patients major ventricular arrhythmias are associated with and perhaps caused by sustained and selective cardiac sympathetic activation. We speculate that depressed ventricular function was present before the ventricular arrhythmia occurred, and that this resulted in reflex cardiac sympathetic activation, which in turn contributed to the genesis of the arrhythmia.
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Meredith et al. (1991) studied this question.
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