Why the study?
Does untreated heart failure exhibit increased neuroendocrine activity compared to healthy individuals?
Population
60 consecutive untreated patients with dyspnoea and a clinical suspicion of heart failure
Design
Cross-sectional
Authors
Loading...
May reflect selective early activation in untreated HF; hypothesis-generating and should not yet change practice.
Does untreated heart failure exhibit increased neuroendocrine activity compared to healthy individuals?
Untreated heart failure is associated with early activation of atrial natriuretic peptide and catecholamines, but not the renin-angiotensin-aldosterone system.
Remes et al. (1991) studied this question.
Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context: