Why the study?
Do microvascular obstruction and intramyocardial hemorrhage predict contractile recovery in reperfused myocardial infarction?
Do microvascular obstruction and intramyocardial hemorrhage predict contractile recovery in reperfused myocardial infarction?
Microvascular obstruction and intramyocardial hemorrhage identified by CMR are strong independent predictors of impaired contractile recovery following reperfused myocardial infarction.
MO/IMH assessment on CMR may refine post-MI recovery prediction beyond infarct size; leaves open therapeutic targeting in prospective studies.
Strain improves within the infarct zone overall following reperfusion with or without MO or IMH. Mid-myocardial and endocardial infarct contractility is diminished in the presence of MO, and further in the presence of IMH. MO and IMH are greater independent predictors of infarct zone contractile recovery than infarct volume or transmural extent.
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Kidambi et al. (2013) studied this question.
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