Why the study?
Does toxicological urine screening effectively detect low adherence in patients with apparent resistant hypertension?
Does toxicological urine screening effectively detect low adherence in patients with apparent resistant hypertension?
Toxicological urine screening is a valuable tool for identifying low adherence, which is the leading cause of apparent resistant hypertension.
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Low adherence predominates in uncontrolled hypertension; supports adherence assessment but leaves open routine screening utility.
Low adherence was the most common cause of poor blood pressure control in patients with apparent resistant hypertension, being twice as frequent as secondary causes of hypertension. Incomplete adherence was far more common than complete nonadherence; thus, assessment of adherence in patients on multiple drug regime is only reliable when all drugs are included in assessment. Assessing adherence by toxicological urine screening is a useful tool in detecting low adherence, especially in the setting of multidrug regimen as a cause of apparently resistant hypertension.
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Jung et al. (2013) studied this question.
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