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udden cardiac death is a common outcome of several cardiac disorders such as acute myocardial ischemia, myocardial infarction, and heart failure. 2] In 1992, using the phenotypes observed in the IVF registry, we advanced the hypothesis that IVF could be the manifestation of concealed forms of arrhythmogenic disorders 5 exacerbated by appropriate triggers. A few years later, the discovery of the genes of long-QT syndrome (LQTS) 6 -8 and the detection of incomplete penetrance 9 supported this early hypothesis.
Napolitano et al. (Mon,) studied this question.