Instantaneous pressure-volume relation of the ejecting canine left atrium.

View Full Paper

Ask AI

Bookmark

Population

10 isolated supported canine left atria

Design

Preclinical

Authors

Discussion

Does not support clinical use of load-insensitive atrial elastance; leaves open translational validation in humans.

Population

10 isolated supported canine left atria

Intervention

Coupling to a real-time computer-simulated ventricle and simulated venous impedance network via a volume servo-pump

Outcome

Instantaneous pressure-volume relation (time-varying elastance E(t) and volume-axis intercepts VO(t))surrogate

Time-varying elastance and volume-axis intercepts provide a load-insensitive characterization of left atrial systolic pump function.

Alexander et al. (1987) studied this question.

View Full Paper

Ask AI

Bookmark