February 7, 2006Circulation
Mitral and Aortic Annular Calcification Are Highly Associated With Systemic Calcified Atherosclerosis
Why the study?
Is atherosclerotic calcification in multiple vascular areas associated with aortic or mitral annular calcification independent of traditional risk factors in asymptomatic patients?
Population
1,242 consecutive asymptomatic patients free of clinical coronary heart disease
Design
Cross-sectional
Authors
Discussion
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Member takes
Implication
Supports independent vascular-valvular links in asymptomatic patients; hypothesis-generating and should not yet change practice.
Structured PICO
Is atherosclerotic calcification in multiple vascular areas associated with aortic or mitral annular calcification independent of traditional risk factors in asymptomatic patients?
P
Population
1,242 consecutive asymptomatic patients free of clinical coronary heart disease
I
Intervention
Presence and extent of atherosclerotic calcification in 5 distinct vascular beds assessed by electron-beam computed tomography
O
Outcome
Prevalent calcification in the aortic and mitral annulisurrogate
Aortic and mitral annular calcification are strongly associated with systemic atherosclerotic calcification in other vascular beds, independent of traditional cardiovascular risk factors.
Cite This Study
Allison et al. (2006) studied this question.