What question did this study set out to answer?

This research examines how blood pressure, serum cholesterol, and smoking contribute to mortality from coronary heart disease, particularly analyzing variations by age.

January 1, 1992Archives of Internal Medicine

Serum cholesterol, blood pressure, cigarette smoking, and death from coronary heart disease. Overall findings and differences by age for 316,099 white men. Multiple Risk Factor Intervention Trial Research Group

View Full Paper

Ask AI

Bookmark

Authors

JNJames D. NeatonPreventive Cardiology

Discussion

Member takes

Implication

Randomized trial assesses heart disease death influences in men, indicating vital health predictors across ages.

Key Points

This research examines how blood pressure, serum cholesterol, and smoking contribute to mortality from coronary heart disease, particularly analyzing variations by age.
Followed 316,099 men in a randomized trial over an average of 12 years.
Identified 6327 deaths from coronary heart disease.
Analyzed relationships between blood pressure, cholesterol levels, and smoking status.
Serum cholesterol levels above 4.65 mmol/L and systolic BP above 110 mm Hg were strongly associated with increased CHD mortality.
Smokers in the highest quintiles of serum cholesterol and systolic BP had CHD death rates approximately 20 times higher than non-smokers in the lowest quintile.
Systolic BP was confirmed as a stronger predictor of CHD death compared to diastolic BP across all age groups.

Cite This Study

James D. Neaton (1992) studied this question.

synapsesocial.com/papers/69f53e9de0fbb6efbd20373e https://doi.org/10.1001/archinte.152.1.56

View Full Paper

Ask AI

Bookmark

Serum cholesterol, blood pressure, cigarette smoking, and death from coronary heart disease. Overall findings and differences by age for 316,099 white men. Multiple Risk Factor Intervention Trial Research Group

Discussion

Member takes

Implication

Key Points

Cite This Study

Serum cholesterol, blood pressure, cigarette smoking, and death from coronary heart disease. Overall findings and differences by age for 316,099 white men. Multiple Risk Factor Intervention Trial Research Group

Discussion

Member takes

Implication

Key Points

Cite This Study

Also Consider

Also Consider