Pulmonary capillary wedge pressure during exercise and long-term mortality in patients with suspected heart failure with preserved ejection fraction

355 patients with unexplained dyspnoea and suspected heart failure with preserved ejection fraction (HFpEF), mean age 61.2 ± 11.3 years, 66.2% women.

Invasive haemodynamic stress test measuring pulmonary capillary wedge pressure (PCWP) at rest and PCWP response to exercise (PCWL, expressed as ratio of PCWP at peak exercise to workload normalized to body weight)

Patients with low PCWP at rest (≤ 12 mmHg) and low PCWL (≤ 25.5 mmHg/W/kg)

Long-term mortality (10-year mortality)hard clinical