In patients with ESRD on chronic hemodialysis, older age and higher PTH levels are independently associated with aortic valve narrowing.
Answers are grounded in this paper and cite their sources.
Higher PTH linked to aortic narrowing in hemodialysis; hypothesis-generating, needs prospective trials before clinical consideration.
BACKGROUND: The aim of this study was to assess the echocardiographic characteristics of chronic hemodialysis (HD) patients with end-stage renal disease (ESRD) in a multicenter prospective cohort study. METHODS AND Patients were divided into 3 groups according to AVA index tertile: group 1, highest tertile; group 2, middle tertile; and group 3, lowest tertile. Group 3 was older, had a greater cardiothoracic ratio on chest X-ray, higher plasma brain natriuretic peptide and total LV afterload, and lower stroke volume index than the other 2 groups. Age and intact parathyroid hormone (PTH) level were independently associated with low AVA index. CONCLUSIONS: Patients with ESRD on chronic HD have a high prevalence of cardiac structural and functional abnormalities including calcified aortic sclerosis. High age and PTH were associated with aortic valve narrowing in these patients.
No takes yet. Share an insight, caveat, or question.
Matsuo et al. (2017) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: