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The aim is to identify and describe the novel HLA-DQB1*06:552 allele resulting from a specific nucleotide substitution.

May 8, 2026HLA

Discovery of the Novel HLA‐DQB1*06:552 Allele in a Taiwanese Individual

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The aim is to identify and describe the novel HLA-DQB1*06:552 allele resulting from a specific nucleotide substitution.
Analysis of HLA-DQB1 alleles in a Taiwanese individual.
Identification of a single nucleotide substitution in codon 109 of HLA-DQB1*06:01:01:01.
Identification of the novel HLA-DQB1*06:552 allele due to a nonsynonymous nucleotide substitution.

Discovers the novel HLA-DQB1*06:552 allele through identifying a nucleotide substitution in a Taiwanese individual, highlighting genetic diversity.

A single nonsynonymous nucleotide substitution in codon 109 of HLA-DQB1*06:01:01:01 results in the novel HLA-DQB1*06:552 allele.

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Yang et al. (2026) studied this question.

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Discovers the novel HLA-DQB1*06:552 allele through identifying a nucleotide substitution in a Taiwanese individual, highlighting genetic diversity.

A single nonsynonymous nucleotide substitution in codon 109 of HLA-DQB1*06:01:01:01 results in the novel HLA-DQB1*06:552 allele.