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The aim is to identify and characterize the novel null allele HLA-DQB1*03:615N found in a Taiwanese individual.

May 15, 2026HLA

HLA‐DQB1*03:615N , a Novel Null Allele Discovered in a Taiwanese Individual

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The aim is to identify and characterize the novel null allele HLA-DQB1*03:615N found in a Taiwanese individual.
Genetic sequencing to identify mutations in the HLA-DQB1 gene.
Analysis of nucleotide substitutions to determine allele variability.
Identified a single nucleotide substitution at codon 118.
Characterized the new allele designated HLA-DQB1*03:615N.

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Genetic analysis uncovers a new null allele in HLA-DQB1*03:01:01:01, suggesting implications for genetics.

A single nucleotide substitution in codon 118 of HLA-DQB1*03:01:01:01 results HLA-DQB1*03:615N.

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Yang et al. (2026) studied this question.

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Genetic analysis uncovers a new null allele in HLA-DQB1*03:01:01:01, suggesting implications for genetics.

A single nucleotide substitution in codon 118 of HLA-DQB1*03:01:01:01 results HLA-DQB1*03:615N.